San Francisco is well endowed with cultural sights, from museums to historic buildings and architectural landmarks like the Golden Gate Bridge and Fisherman's Wharf.
Highlights include Alcatraz, one of the nation’s most infamous former prisons, Golden Gate National Recreation Area (made up of assorted gardens, museums, trails and recreational facilities), the Embarcadero esplanade, colorful Chinatown, the museums of SoMa (South of Market), sunny Mission District and the steep streets of Russian Hill.
In short - give yourself several days at least to enjoy a brief introduction to San Francisco's many (and varied) charms.